Melanoma
Dose recommendation
Safety Profile
Below is a selection of the observed side effects; please refer to the SmPc or the package leaflet for the complete list.
Myelosuppression
Patients who develop anaemia may need blood transfusions. Dose adjustment or...Twitter Linkedin Facebook Pinterest Google plusEfficacy
Indications
Myelofibrosis (MF) Jakavi is indicated for the treatment of disease-related splenomegaly or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post polycythaemia vera...
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Mechanism of Action
Uncontrolled JAK/STAT signalling is characteristic of both polycythaemia vera (PV) 1–5 a nd for myelofibrosis (MF). 6
JAKs are tyrosine kinases that transmit signals from cytokine or growth factor receptors to the cell...Twitter Linkedin Facebook Pinterest Google plusIndication
Rydapt ® (midostaurin) is indicated: 1
In combination with standard induction therapy with daunorubicin and cytarabine as well as high-dose consolidation chemotherapy with cytarabine, followed by midostaurin maintenance...Twitter Linkedin Facebook Pinterest Google plusIndication
KISQALI is indicated for the treatment of women with hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) negative locally advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant as...
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