Dosing / administration
In adults, the recommended dose of Gilenya is one 0.5 mg capsule taken orally once daily.
In paediatric patients (10 years of age and above), the recommended dose is dependent on body weight:
Paediatric patients with...Twitter Linkedin Facebook Pinterest Google plusExjade®
Rydapt AML
Psoriasis
Mechanism of Action
Midostaurin inhibits the activity of various receptor tyrosine kinases, including FLT3 and KIT kinase. 1-6 Midostaurin binds to the catalytic portion of multiple receptor tyrosine kinases, including: 1
FLT3 (ITD, TKD and...Twitter Linkedin Facebook Pinterest Google plusDosage recommendations
Treatment with midostaurin should be initiated by a physician experienced in the use of medicine for cancer. 1
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Before starting treatment
Molecular diagnosisThe presence of the FLT3 mutation (internal tandem duplication [ITD] or tyrosine kinase domain [TKD]) must be confirmed, prior to a patient with AML receiving midostaurin, using a validated test. 1 The...
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Check the number of white blood cells regularly 1 For signs and symptoms of infection, including infections related to infusions and catheters. If an infection has been diagnosed, appropriate treatment should be instituted immediately,...Twitter Linkedin Facebook Pinterest Google plus
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