Indications - Cosentyx PsA
Cosentyx (generic name: secukinumab) is a medication used to treat several autoimmune conditions. Here are the key indications for Cosentyx:
1. Plaque Psoriasis:
For adults with moderate to severe...
Cosentyx (generic name: secukinumab) is a medication used to treat several autoimmune conditions. Here are the key indications for Cosentyx:
1. Plaque Psoriasis:
For adults with moderate to severe...
Uncontrolled JAK/STAT signalling is characteristic of both polycythaemia vera (PV) 1–5 and for myelofibrosis (MF). 6
JAKs are tyrosine kinases that transmit signals from cytokine or growth factor receptors to the cell...The efficacy and safety 5 of iptacopan in adult patients with PNH were evaluated in two multicentre, open-label, 24-week phase III studies: an active comparator-controlled study (...
Kesimpta is indicated for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS) with active disease defined by clinical or imaging features 1
Both newly diagnosed patients and patients switching from...
Mechanism of Action (MoA)¹
Iptacopan is a proximal complement inhibitor that targets Factor B (FB) to selectively inhibit the alternative pathway of the complement cascade. Inhibition of FB in the...
Below is a selection of the observed side effects; please refer to the SmPc or the package leaflet for the complete list.
Myelosuppression
Patients who develop anaemia may need blood transfusions. Dose adjustment or...Cosentyx (secukinumab) is a fully human IgG1/κ monoclonal antibody that selectively binds to and neutralizes the proinflammatory cytokine interleukin-17A (IL-17A). 1 Cosentyx works by targeting IL-17A and inhibiting its interaction with...