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  • Dosing - Entresto

    Dose regimen Oral use Twice daily dose. Can be taken with or without food; The tablets must be swallowed with a glass of water. Tablet strength makes interim dose adjustment easy. If a dose is missed, the patient should take the next...
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  • Reimbursement / eHealth - Entresto

    Entresto ® is reimbursed for the treatment of adult patients with chronic heart failure with reduced ejection fraction in Belgium.

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  • PARADIGM-HF

    PARADIGM-HF is the largest study to date in heart failure patients. 1

    Summary:

    The PARADIGM-HF study on systolic heart failure with 8,399 patients in NYHA class II-IV. 2,3...

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  • PIONEER-HF

    The recently presented PIONEER-HF studies the efficacy and safety of initiating ENTRESTO compared to enalapril prior to discharge after hospitalization for an acute decompensated heart failure episode. 1 The results of PIONEER-HF...

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  • Efficacy - Entresto

    ENTRESTO ® achieved superior outcomes vs Enalapril in the largest trial ever conducted in HF
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  • Dosing

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  • Mechanism of Action

    TPO is the main cytokine involved in regulation of megakaryopoiesis and platelet production, and is the endogenous ligand for the TPO-R.
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  • Patient Resources

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  • Mechanism of Action - Entresto

    Sacubitril/valsartan, a first-in-class ARNI, delivers simultaneous inhibition of neprilysin and blockade of the AT1 receptor. Sacubitril/valsartan is a sodium salt complex comprising sacubitril (AHU377), a prodrug, which is further metabolized to the...

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  • Cosentyx zelf-injectie gids

      Download Dutch version     .field-name-field-np4-expiry-date {display:none;}
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